DOUBLE FUNCTION CYTOCHROMES P450 OF THE CYP74 FAMILY

Original title

ДУАЛИСТИЧНЫЕ ЦИТОХРОМЫ P450 ПОДСЕМЕЙСТВА CYP74B

Authors

E.K. Bessolitsyna, S.S. Gorina, Y.Y. Toporkova, L.Sh. Mukhtarova, A.N. Grechkin

Contact information

Kazan Institute of Biochemistry and Biophysics of Kazan Science Center of the Russian Academy of sciences, Kazan, Russia, Kazan, Этот адрес электронной почты защищён от спам-ботов. У вас должен быть включен JavaScript для просмотра.

Pages

1187-1190

DOI

10.31255/978-5-94797-319-8-1187-1190

Abstract

The CYP74B subfamily of fatty acid hydroperoxide transforming enzymes includes 13-hydroperoxide specific hydroperoxide lyases (HPLs) and divinyl ether synthases (DESs). The objects of the present work are the recombinant CYP74B3 (Solanum tuberosum), CYP74B4v1 (Medicago sativa), CYP74B6 (Cucumis sativus), and CYP74B16 (Linum usitatissimum) enzymes. Along with major products these enzymes produced oxiranyl carbinols. The preferred substrates of these enzymes are 13-hydroperoxides of linoleic and α-linolenic acids.