ADP/ATP TRANSLOCATOR AND CELL REACTION ON STRESS EXPOSURE

Original title

АДФ/АТФ ТРАНСЛОКАТОР И РЕАКЦИЯ КЛЕТКИ НА СТРЕССОВОЕ ВОЗДЕЙСТВИЕ

Authors

E.G. Rikhvanov, I.F. Fedoseeva, N.N. Varakina, T.M. Rusaleva, A.V. Fedyaeva, A.V. Stepanov, G.B. Borovskii

Contact information

Siberian Institute of Plant Physiology and Biochemistry SB RAS, Irkutsk

Pages

103-105

DOI

10.31255/978-5-94797-318-1-103-105

Abstract

Heat shock was shown to induce a transient hyperpolarization of inner mitochondrial membrane in yeast cells, which was important for induced thermotolerance and heat shock proteins synthesis. Hyperpolarization was known to be dependent on mitochondrial ADP/ATP ratio. Therefore, the role of ADP/ATP translocator in heat shock response has been studied. It was shown that deletion of genes encoding ADP/ATP translocator abolished the development of induced thermotolerance, but did not affect Hsp104 synthesis. Moreover, a loss of ADP/ATP translocator increased the heat-shock induced hyperpolarization.